CSIR plans genome sequencing to map population diversity

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Council of Scientific and Industrial Research (CSIR) has planned to roll out a major mission to sequence the genes of a 1,000 rural youth across India aims at educating a generation of students on the significance of genomics.

Key Facts of the Project:

  • The project is an adjunct to a much larger government-led programme, still in the works, to sequence at least 10,000 Indian genomes.
  • The project aims at educating a generation of students on the “usefulness” of genomics and has been taken for the first time on a large scale in India.
  •  Globally, many countries have undertaken genome sequencing of a sample of their citizens to determine unique genetic traits, susceptibility (and resilience) to disease.
  •  Those recruited as part of genome-sample collections are representative of the country’s population diversity and bulk of them will be college students, both men and women, and pursuing degrees in the life sciences or biology.

About Institute of Genomics and Integrative Biology:

  •  CSIR-Institute of Genomics & Integrative Biology (IGIB) is a premier Institute of Council of Scientific and Industrial Research (CSIR), engaged in research of national importance in the areas of genomics, molecular medicine, bioinformatics and proteomics.
  •  It’s mission: “To translate concepts developed in basic biological research to commercially viable technologies for health care”

Methodology:

  • Genomes will be sequenced based on a blood sample and the scientists plan to hold at least 30 camps covering most States.
  • Every person whose genomes are sequenced will be given a report. The participants would be told if they carry gene variants that make them less responsive to certain classes of medicines. For instance, having a certain gene makes some people less responsive to clopidogrel, a key drug that prevents strokes and heart attack.
  • The project would involve the Hyderabad-based Centre for Cellular and Molecular Biology (CCMB) and cost ₹18 crore, with the sequencing to be done at the IGIB and the CCMB.

Source: The Hindu

Probable Question:

Consider the following statements with regards to Genome sequencing

I. It means determining the order of the four chemical building blocks – called “bases” – that make up the DNA molecule.

II. It helps to determine unique genetic traits, susceptibility, and resilience to diseases.

III. IIT Madras has planned to roll out a mission to sequence the genes of a 1,000 rural youth across India.

IV. The project aims at educating a generation of students on the significance of genomics.

Which of the following statement’s is/are true?

A. I and II

B. I, II and III

C. I, II and IV

D. All of these

 

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